| Clinics and Pathology |
| Disease | Acute non lymphocytic leukemia (ANLL) |
| Note | poorly known: only 2 cases to date |
| Phenotype / cell stem origin | a case of Fanconi anemia and a case of M1-ANLL |
| Epidemiology | The Fanconi anemia patient was a 9 yr old girl, and the ANLL case was a 22 yr old male patient |
| Prognosis | unknown |
| Cytogenetics |
| Cytogenetics Morphological | The t(1;16) presented as a der(16)t(1;16) in the 2 cases, resulting in trisomy 1q. The t(1;16) was the sole anomaly in each case. |
| External links |
| Other database | t(1;16)(q12;q24) | Mitelman database (CGAP - NCBI) | |
| Other database | t(1;16)(q12;q24) | CancerChromosomes (NCBI) |
| To be noted |
| Additional cases are needed to delineate the epidemiology of this rare entity: you are welcome to submit a paper to our new Case Report section. |
| Bibliography |
| Fluorescence in situ hybridization analysis of chromosome 1 abnormalities in hematopoietic disorders: rearrangements of DNA satellite II and new recurrent translocations. |
| Busson-Le Coniat M, Salomon-Nguyen F, Dastugue N, Maarek O, Lafage-Pochitaloff M, Mozziconacci MJ, Baranger L, Brizard F, Radford I, Jeanpierre M, Bernard OA, Berger R |
| Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 1999 ; 13 (12) : 1975-1981. |
| PMID 10602418 |
| Contributor(s) |
| Written | 02-2000 | Jean-Loup Huret |
| Citation |
| This paper should be referenced as such : |
| Huret JL . t(1;16)(q12;q24). Atlas Genet Cytogenet Oncol Haematol. February 2000 . URL : http://AtlasGeneticsOncology.org/Genes/t0116q12q24ID1318.html |
| © Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Sat Dec 6 18:02:10 2008 |
For comments and suggestions or contributions, please contact us