Atlas of Genetics and Cytogenetics in Oncology and Haematology
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GROUPE FRANCAIS DE CYTOGENETIQUE HEMATOLOGIQUE (GFCH)
[French Version]
Created in 1979 by J Tanzer, J Fraisse, R Berger, and H Van Den Berghe, the
GFCH is part of the Société Française d'Hématologie (French society of
haematology). In 1998, the GFCH federates 50 laboratories from France,
Belgium, Switzerland, and Morocco. All GFCH works are cooperative, and its
original working method (double revision of Cytogenetics files in regional
and national workshops) is a guarantee of quality. The GFCH pubishes (see
below) as a group, and has become a reference for the constitution of other
similar groups in other European countries. There are 3 meetings a year,
providing long acquaintances between hospital cytogeneticists, clinicians,
and researchers. Our works have clinical, fundamental, and nosological
values,
as cytogenetics has provided deep insights in leukaemogenesis, and shows a
renewed powerful potential with molecular cytogenetics. Subjects under
study in 1998 are chronic lymphoid leukaemia, multiple myeloma,
megakaryocytic leukaemias, chromosome 12 anomalies in myeloid malignancies,
and chromosomes 5 and 7 rearrangements. The GFCH organizes thematic
sessions at the congresses of the French society of haematology. A quality
assessement scheme is under study since 1997.
Secretary
Pr Philippe BERNARD
Laboratoire d'Hématologie, Université Victor Segalen Bordeaux 2
146, rue Léo Saignat, 33076 Bordeaux Cedex
Tel : 05 57 57 15 81 Fax : 05 56 51 42 18
E-mail : Philippe.Bernard@hematologie.u-bordeaux2.fr
PUBLICATIONS LIST
- 1. Cytogénétique Hématologique. Pathologie Biologie, 1982 , 30: Numéro spécial.
- 2. Chromosomal analysis of 63 cases of secondary nonlymphoid blood disorders : a cooperative study.
Cancer Genetics and Cytogenetics, 1984,12:95-104. Chair : R Berger.
- 3. Chromosome analysis of 120 cases of chronic myelomonocytic leukemia : a
cooperative study.
Cancer Genetics and Cytogenetics, 1986, 21:11-30. Chair : J-L Michaux
- 4. Cytogenetics of acutely transformed chronic myeloproliferative syndromes
without a Philadelphia chromosome.
Cancer Genetics and Cytogenetics, 1988, 32: 157-168. Chair : Ph Bernard
- 5. Cytogenetic findings in leukemic cells of 56 patients with
constitutional chromosome abnormalities. A cooperative study.
Cancer Genetics and Cytogenetics, 1988, 35:243-252. Chair : M-F Bertheas
- 6. Cytogenetics might elucidate the etiology of acute transformation of
chronic myeloproliferative syndromes without a Philadelphia chromosome.
European Journal of Hematology, 1989, 43:86-87. Chair : Ph Bernard
- 7. Acute myelogenous leukemia with an 8;21 translocation. A report on 148
cases from the Groupe Français de Cytogénétique Hématologique.
Cancer Genetics and Cytogenetics, 1990, 44:169-179. Chair : A Bernheim
- 8. (p13-14;q14-21) : A new recurrent translocation in T-cell acute lymphoblastic leukemia.
Genes, Chromosomes & Cancer, 1991, 3:411-415. Chair: N Dastugue
- 9. Isochromosome 21q in hematologic malignancies.
Cancer Genetics and Cytogenetics, 1991, 55:101-105. Chair : S Raynaud
- 10. Chronic Myelomonocytic leukemia : single entity or heterogeneous
disorder? A prospective multicenter study of 100 patients.
Cancer Genetics and Cytogenetics, 1991, 55:57-65. Chair : J-L Michaux
- 11. Philadelphia-negative (Ph-) chronic myeloid leukemia (CML) : comparison
with Ph+ CML and chronic myelomonocytic leukemia.
Blood, 1991, 78:205-211. Chair : J-L Michaux
- 12. Collaborative study of karyotypes in childhood acute lymphoblastic
leukemias.
Leukemia, 1993, 7:10-19. Chair : M-J Grégoire, N Dastugue
- 13. Acute leukemia treated with intensive chemotherapy in patients with a
history of previous chemo- and/or radiotherapy. Prognostic significance of
karyotype and preceding myelodysplastic syndrome.
Leukemia, 1994, 8:87-91. Chair : H Weh
- 14. Cytogenetic abnormalities in adult acute lymphoblastic leukemia :
correlations with clinical findings and outcome. A collaborative study of
the Groupe Français de Cytogénétique Hématologique.
Blood, 1996, 87 : 3135-3142. Chair : C Charrin, N Dastugue
- 15. Cytogenetic analysis in patients with primary myelodysplastic syndromes
in leukemic transformation : a report on 94 cases.
Hematology and Cell Terapy, 1996, 38 : 177-181. Chair : Ph Jonveaux
- 16. Forty-four cases of childhood myelodysplasia with cytogenetics,
documented by the Groupe Français de Cytogénétique Hématologique.
Leukemia,1997, 11 : 1478 - 1485. Chair : C Leonard & J-L Huret.
STUDIES IN PROGRESS
- Translocations t(11;14) Chair : C Bastard
- Myeloma Chair : N-V Smadja
- Chronic Lymphoid Leukaemia Chair : D Leroux
- Promyelocytic Leukaemias without t(15;17) Chair : M Lafage-Pochitaloff
- Acute Megakaryocytic Leukaemias Chair : N Dastugue
- Bi-nucleated Lymphocytes. Chair : H Mossafa
- Chromosome 12 Anomalies in MDS/ANLL Chair : C Bilhou-Nabéra
- Chromosomes 5 and 7 Rearrangements using F.I.S.H. Chair : M Lessard
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